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Public procurement
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ocds-h6vhtk-05a434Published facts
050045-2026The All Wales Medical Genomics Service (AWMGS) has routinely utilised Multiplex Ligation-Dependent Probe Amplification (MLPA) as a diagnostic tool for identifying Copy Number Variations (CNVs)—including deletions and duplications—across a range of genetic disorders. This testing supports clinical decision-making and patient treatment strategies.MLPA technology involves the use of oligonucleotide probe pairs that hybridise to specific DNA sequences within target genes. When both probes bind adjacently at a site of interest, they are ligated and subsequently amplified via Polymerase Chain Reaction (PCR). The amplified DNA fragments are then separated by capillary electrophoresis and analysed to detect CNVs.Since its inception, AWMGS has exclusively sourced MLPA probes and reagents from MRC Holland, a Netherlands-based supplier recognised for its specialised products in molecular diagnostics.
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Award notice observed
Latest variant observed by Bidwake on .
Open this official Find a Tender notice
060578-2025Award notice observed
Latest variant observed by Bidwake on .
Open this official Find a Tender notice
050045-2026Awards and suppliers
Buyer: Cardiff and Vale University Health BoardSupplier: MRC Holland
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