Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

Published facts

What the notice says

Buyer

NHS England

Published status

complete

Latest release reference

089823-2026

CPV codes

Common Procurement Vocabulary (CPV) codes: 85100000

Published tags

award, contract

Latest record Bidwake loaded from this source

25 Sept 2026

Intention to award the Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service. <br/><br/>This is a a one-time, in vivo gene replacement therapy, for use in babies aged 12 months and under, that utilises an adeno-associated virus serotype 9 (AAV9) vector, modified to contain a functional copy of the human SMN1 gene. It is administered intravenously, allowing the vector to deliver the gene into motor neurones and peripheral tissues, enabling the sustained expression of survival motor neuron (SMN) protein, which is deficient or mutated in individuals with SMA.<br/><br/>Onasemnogene abeparvovec intrathecal (OAV101 IT) is a one-time in vivo gene replacement therapy for patients with SMA, proposed to treat individuals with SMA aged 2 years and over. This intrathecal injection will be used to treat a distinct cohort of SMA patients to Zolgensma. It will be assessed via NICE’s technology appraisal programme, with an expected final guidance publication date in late 2026.<br/><br/>Procurement was carried out in Lots for the services as detailed above. Contract values are estimated and will be dependent on number of patients actually treated at each awarded provider.

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Observed notice trail

How the published record developed

Events follow the publisher date where one is available. “Seen by Bidwake” is the date this service first found the record.

1. Award notice observed

   22 Sept 2026

   Latest variant observed by Bidwake on 25 Sept 2026.

   Open this official Find a Tender notice

   Record references

   Release reference

   089823-2026

   Published tags

   award, contract

Awards and suppliers

Published award and contract facts

• Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

  Buyer: NHS EnglandSupplier: UNIVERSITY HOSPITALS BRISTOL AND WESTON NHS FOUNDATION TRUST

  End date in notice

  Date not published

  Value shown in notice

  £1,036,000Value from the linked contract

  Official source

  Open the official Find a Tender notice for Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

  About this figure

  • This figure comes from the linked contract record. Overall totals continue to use the separately published award value.

  View record references

  Source

  Find a Tender

  Award or lot reference

  089823-2026-1

• Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

  Buyer: NHS EnglandSupplier: Great Ormond Street Hospital

  End date in notice

  Date not published

  Value shown in notice

Related evidence

Published terms and linked processes

• Options are statedLot 1

  Commissioners have the option to extend the contract for a further two years

  Published 22 Sept 2026.Open supporting notice 089823-2026
• Options are statedLot 2

  Commissioners have the option to extend the contract for a further two years

  Published 22 Sept 2026.Open supporting notice 089823-2026
• Options are statedLot 3

  The commissioners have the option to extend for a further 2 years

  Published 22 Sept 2026.Open supporting notice 089823-2026

No exact source-published process relationship was found.